American study found that the virus had mutated four months ago and became more infectious, making it difficult for vaccines to cope

According to a study by Los Alamos National Laboratory in the United States, the new coronavirus that appeared more than four months ago has been mutated. The new major virus that spreads in the United States seems to be more infectious. Will further mutate and affect the effectiveness of the vaccine research and development work that scientists have undertaken

In May, the spread of the fierce epidemic in the United States has slowed, vaccine research and development has also progressed, and the economic restart has been put on the agenda. However, a recent study recently published by the Los Alamos National Laboratory in the United States has caused new changes in the public’s perception of the risk of new coronavirus mutations and infections, and new concerns about the possibility of repeated epidemics and their harm.

The data updated by the New York State Government on the evening of May 6th shows that 20597 people have been diagnosed with New Coronary Pneumonia in New York State, about 85% of whom are over 60 years old. New York State Governor Como said at the epidemic conference that day that 66% of newly admitted patients with new coronary pneumonia were infected at home and without frequent going out, saying “this is surprising.” This data is based on a survey of approximately 1,000 patients in 100 hospitals across the state.

Other outbreak indicators released by Como on the same day showed that the total number of hospitalizations in New York State on the 5th was 9,179, which was less than 10,000 for the fourth consecutive day; there were 601 new patients with new coronary pneumonia who were hospitalized, which declined for the fifth consecutive day. New York City Mayor Bai Sihao ’s data released that day showed that New York City had 109 new patients with new coronary pneumonia who were hospitalized on the 4th, an increase of 34 from the 3rd; the number of intensive care patients was 599, an increase of 3 from the 3rd; a positive virus test The rate was 15%, 7 percentage points lower than the 3rd.

According to Johns Hopkins University data, about 25,600 people with new coronary pneumonia are currently dying in New York State. “The New York Times” believes that the extra part of the deceased should not have been tested for viruses, but the symptoms before death coincided with the new coronary pneumonia, which was classified by New York State officials as suspected of dying of the new coronary pneumonia, and the number of deaths of the diagnosed.

A notable feature of the economic crisis caused by the epidemic is the rate of decline in economic growth. Jeffrey Young, former global head of foreign exchange at Citigroup and co-founder and CEO of DeepMacro, pointed out to Caijing reporters that Seattle and New York City began to expand social relations for the first time from early March to mid-March By the distance policy, by April 1, the “people-to-people” business activity had collapsed. In contrast, the global financial crisis began in the summer of 2007 and slowly spread from one institution to another, weakening economic growth until the bankruptcy of Lehman Brothers in September 2008-more than a year after the economic crisis broke out, the economy Before it finally collapsed, New Coronary Pneumonia was more contagious and destructive than the global financial crisis-the impact on economic growth was significantly faster and greater.

The number of diagnosed new American crowns has now exceeded 1.21 million. The new coronavirus continues to wreak havoc in most parts of North America, Europe and parts of the Middle East. According to data from Johns Hopkins University, on Wednesday, May 6, the number of diagnoses worldwide exceeded 3.72 million, and the death toll caused by the new coronavirus rose to more than 261,000.

According to data provided by Johns Hopkins University, the death toll in the United States exceeds 72,000, close to 30% of the global total. According to the analysis of the US media, in the 24 hours ending at 8 pm on Tuesday, May 5, the United States added 2,100 new deaths, the highest in a week.

Since the end of March, the number of new deaths announced every day in the United States has far exceeded 1,000, and the number of newly diagnosed people has exceeded 20,000. A closely watched model predicts that the number of deaths may nearly double by early August. Why has the epidemic in the United States remained high? Recently, the Los Alamos National Laboratory (Los Alamos National Laboratory) research found that in a sense to provide an explanation.

Research at Los Alamos National Laboratory believes that the new coronavirus has become more contagious after mutation. On April 30th, Los Alamos National Laboratory published a 33-page report on the BioRxiv archives network, which believed that the coronavirus that appeared in Wuhan, China, more than four months ago has been mutated. The mutated virus strain began to spread in Europe in early February, and then spread to the United States and Canada, etc., until the end of March became the main virus strain of global infection cases. This major virus strain circulating in the United States seems to be more infectious.

The laboratory collaborated with Duke University in the United States and The University of Sheffield in the United Kingdom. After analyzing thousands of new coronavirus sequences, it was determined that the virus currently has 14 variants.

The US media quoted the lead author of the study and the computational biologist Bette Korber as saying on Facebook, “This is bad news, but please don’t be frustrated by this matter. Our laboratory team published Regarding the report, only because clinical staff and experimental teams around the world are working hard to create new virus sequences for their communities as soon as possible, so we cannot ignore this. “

This research report has not yet been peer-reviewed, but the researchers emphasized that considering that more than 100 vaccines are being developed against new coronaviruses worldwide, the news of virus mutations is an “urgent concern”.

Researchers warn that if the new coronavirus does not subside like the seasonal flu in summer, it may mutate further and limit the effectiveness of the new coronavirus vaccine that scientists around the world are developing. Some vaccine researchers have been using viral gene sequences isolated by health authorities early in the outbreak.

The two pharmaceutical companies said on May 5 that their new coronavirus experimental vaccine is about to be sent to the United States for preliminary human trials.

Recently, the US pharmaceutical manufacturer Pfizer Inc and the German biotechnology company BioNTech SE said that the new crown vaccine they jointly developed is ready to start human trials in the United States. If the test proves its safety and effectiveness, the vaccine may be in It is widely distributed in the United States. The vaccine may become one of the first new coronavirus vaccines approved for use in the United States. The two companies say it usually takes years of effort to develop a vaccine, and this vaccine uses messenger ribonucleic acid (mRNA) technology, which is much faster than typical methods.

American biotechnology company Moderna Inc and the US government are collaborating to develop a vaccine that uses similar technologies. The first phase of the vaccine trial is ongoing, and the mid-term trial is scheduled to begin this quarter. Pfizer had previously optimistically stated that the US Food and Drug Administration (FDA) would approve as early as October.

However, Dr. David Nabarro, the British Special Envoy for the New Crown Outbreak in the World Health Organization, warned a few days ago: “We cannot absolutely determine that a vaccine will appear, even if a vaccine is actually developed, it will pass all the effectiveness and safety Sex tests ca n’t be completely determined. ”Dr. Patrick Vallance, the chief scientific adviser of the British government, echoed Nabaro ’s statement, saying that he hopes to develop an effective vaccine, but at the same time the warning may not be soon; All vaccines under development can only be hopeful and require a long-term experimental process.

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