Novel coronavirus can be killed by alpaca antibody?

Say, mention network ancient god beast “grass mud horse” — alpaca.
What images come to mind?

Unruly eyes…

Flowing hair…

And a natural tendency to let go…

But recently, a news from Belgium has brought the animal alpaca back to the social media and the Internet: can you find a powerful antibody against novel coronavirus in this silly creature?

It all started with a four-year-old alpaca named winter in Belgium.
Winter is a female Llama with dark brown fur, spindly legs and long, enviable eyelashes.

“Winter” is injected with a protein found on the surface of a novel coronavirus, which then produces an antibody response. These antibodies seem to be effective in protecting the carrier and eliminating the threat of the virus…

Ancient god beast “grass mud horse” antibody can destroy the new crown?

Antibodies in the blood of alpacas help neutralize novel coronavirus, according to a new study from Belgium, the Sunday times reported.

“Molecules in the blood of an alpaca may play a therapeutic role in novel coronavirus outbreaks,” according to a report by researchers at the Vlaams Institute for Biotechnology in Belgium and researchers in the United States.
The feasibility of using alpaca antibodies deserves further study.”

“Our goal is to find an antiviral therapy that instill antibodies directly into patients,” said dorian devrije, a researcher at the Flemish institute of biotechnology in Belgium.
The first human trials could begin “before the end of this year.”

Alpaca: why me?
What are the specific antibodies in my body?

Antibody is a protein molecule secreted by mature B lymphocytes, known as immunoglobulin.

There are a total of five antibodies in the body, and IgG, the most abundant antibody in the blood, is an example: it has four chains, two light chains and two heavy chains.

Heavy chains are “longer” and therefore “heavier” and have higher molecular weights.
Low molecular weight antibodies can be delivered to the target more easily, but large IgG antibodies in the blood can be difficult to transport to specific tissues.

“Nanoantibodies” have been found in camels, which are much smaller than human antibodies, allowing people to use nanotechnology to deliver drugs using tiny molecules that can more effectively target tiny viruses.

An unexpected discovery in a laboratory at the university of Brussels in 1989 led researchers to learn about the unusual properties of antibodies in the blood of camels, llamas and alpacas.
Initially used in AIDS research, the antibodies have proved effective against a variety of viruses, including recent outbreaks of Middle East respiratory syndrome (Mers) and severe acute respiratory syndrome (Sars).

In alpaca, which belongs to the family camelidae, the monodomain antibody showed its potential in novel coronavirus.

Such as the article mentioned, a Belgium called Winter of alpaca is involved in a project on SARS and MERS (respiratory syndrome) in the Middle East studies, scientists have found that after injection of the corresponding antigen, alpaca produced two types in the body used to hedge against MERS and SARS antibody, respectively, at the same time, the two became double antibody against SARS antibody coupling, neutralization, eliminate will be the potential of coronavirus.
However, it is still not clear whether the conjugated antibody has a protective effect in animals, and further tests are needed to confirm this, which is still some way off.

Two thousand alpacas in the west are on standby

In China, a large alpaca breeding base in Shanxi Province has cooperated with a number of scientific research institutions and is also studying nanoantibodies of alpacas.

This time, the alpaca is likely to become a true “god beast” against the new crown…

The protective effect of alpaca new coronet antibody is not permanent

According to the New York times points out, the researchers hope that eventually alpaca produce antibodies can be used for preventive treatment, namely to uninfected will be coronavirus alpacas new crown antibody injection, in order to protect them from will be coronavirus infection, such as injection of alpacas antibodies to health care providers, and to protect them in the process of treatment COVID – 19 patients infected by patients.

The study stressed that while the protection of the alpaca neocoronal antibody is immediate, its effects are not permanent and can only last for one to two months if the alpaca neocoronal antibody is not injected again.

Alpaca, spit at me!

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